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. 2012 Dec;3(4):219-23.
doi: 10.1007/s13539-012-0090-6. Epub 2012 Nov 16.

Research on cachexia, sarcopenia and skeletal muscle in cardiology

Andrew J S Coats  1
Affiliations

Research on cachexia, sarcopenia and skeletal muscle in cardiology

Andrew J S Coats. J Cachexia Sarcopenia Muscle. 2012 Dec.

Abstract

Background: The awareness of cardiac cachexia, i.e. involuntary weight loss in patients with underlying cardiovascular disease, has increased over the last two decades.

Methods and results: This mini-review looks at recent research in the cardiovascular literature that is relevant to the areas of interest of the Journal of Cachexia, Sarcopenia and Muscle. It identifies significant research in the last 3 years on the obesity paradox, the causes and effects of skeletal muscle wasting, animal models of cachexia and emerging treatment ideas in cardiac cachexia.

Conclusions: Assuming a similar literature in the fields of cancer, chronic obstructive pulmonary disease, chronic renal failure and chronic liver failure, the emergence of cachexia as a vibrant area of clinical and experimental research seems assured.

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References

    1. Marinou K, Tousoulis D, Antonopoulos AS, Stefanadi E, Stefanadis C. Obesity and cardiovascular disease: from pathophysiology to risk stratification. Int J Cardiol. 2010;138:3–8. doi: 10.1016/j.ijcard.2009.03.135. - DOI - PubMed
    1. Thompson AM, Zhang Y, Tong W, et al. Association of obesity and biomarkers of inflammation and endothelial dysfunction in adults in Inner Mongolia, China. Int J Cardiol. 2011;150:247–252. doi: 10.1016/j.ijcard.2010.04.011. - DOI - PMC - PubMed
    1. Younge JO, Damen NL, van Domburg RT, Pedersen SS. Obesity, health status, and 7-year mortality in percutaneous coronary intervention: in search of an explanation for the obesity paradox. Int J Cardiol. 2012. doi:10.1016/j.ijcard.2012.03.105. - PubMed
    1. Trullàs JC, Formiga F, Montero M, the RICA Investigators, et al. Impact of weight loss on mortality in chronic heart failure: findings from the RICA Registry. Int J Cardiol. 2012. doi:10.1016/j.ijcard.2012.09.062. - PubMed
    1. Zamora E, Lupón J, de Antonio M, et al. The obesity paradox in heart failure: is etiology a key factor? Int J Cardiol. 2011. doi:10.1016/j.ijcard.2011.11.022. - PubMed

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