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Case Reports
. 2012 Nov;27(11):1433-5.
doi: 10.3346/jkms.2012.27.11.1433. Epub 2012 Oct 30.

First case of Bartonella quintana endocarditis in Korea

Min Hee Lim  1 , Doo Ryeon Chung, Wook-Sung Kim, Kyung Sun Park, Chang-Seok Ki, Nam Yong Lee, Sang Min Kim
Affiliations
Case Reports

First case of Bartonella quintana endocarditis in Korea

Min Hee Lim et al. J Korean Med Sci. 2012 Nov.

Abstract

Since microbial gene sequencing was utilized for etiologic diagnosis of culture-negative endocarditis, cases of Bartonella endocarditis have been reported in various countries. Herein we report the first case of Bartonella quintana endocarditis, which was confirmed for the first time in Korea by 16S rRNA gene sequencing from the excised valve. A 75-yr-old woman was hospitalized due to dyspnea. Echocardiography demonstrated large oscillating vegetation at the aortic valve. Blood culture was negative. She underwent valve replacement and sequencing of the 16S rRNA gene from excised valve identified Bartonella quintana. She was successfully treated with combined use of ceftriaxone and gentamicin.

Keywords: 16S rRNA; Bartonella quintana; Gene Sequencing; Infective Endocarditis.

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