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Randomized Controlled Trial
. 2012 Aug;26(15):692-3, 696.

[Surgery added with fluconazole in treatment of fungal rhinosinusitis]

[Article in Chinese]
Zhiyuan Zhang  1 , Jian Zhang, Wugen Luo, Hongqun Jiang
Affiliations
  • PMID: 23167181
Randomized Controlled Trial

[Surgery added with fluconazole in treatment of fungal rhinosinusitis]

[Article in Chinese]
Zhiyuan Zhang et al. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Aug.

Abstract

Objective: To explore the effect of surgery added with antifungal agents in treatment of fungal rhinosinusitis.

Method: One hundred and two consecutive patients with fungal rhinosinusitis were randomly divided into two groups: the control group (n=48) were treated with surgery alone, the treatment group (n=54) were treated with surgery plus antifungal therapy during operation and postoperation. The patients were followed up for 6 months and the relapse rates between two groups were compared.

Result: No relapse was observed in the treatment group. The relapse rate of the control group was 20.8% (P < 0.01).

Conclusion: Surgery plus antifungal therapy can prevent the relapse of fungal rhinosinusitis significantly.

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