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Review
. 2013 Jan;9(1):29-36.
doi: 10.1016/j.hfc.2012.09.007. Epub 2012 Oct 11.

Epidemiologic and statistical methods for comparative effectiveness research

Mark A Hlatky  1 , Wolfgang C Winkelmayer, Soko Setoguchi
Affiliations
Review

Epidemiologic and statistical methods for comparative effectiveness research

Mark A Hlatky et al. Heart Fail Clin. 2013 Jan.

Abstract

Observational methods are evolving in response to the widespread availability of data from clinical registries, electronic health records, and administrative databases. These approaches will never eliminate the need for randomized trials, but clearly have a role in evaluating the effect of therapies in unselected populations treated in routine practice.

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Figures

Fig. 1
Fig. 1
Methods for controlling confounding. (Adapted from Schneeweiss S. Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics. Pharmacoepidemiol Drug Saf 2006;15(5):291–303; with permission.)
See this image and copyright information in PMC

References

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