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Comment
. 2012 Dec;265(3):651-3.
doi: 10.1148/radiol.12122038.

Science to practice: a new insight into nephrotoxicity after contrast medium administration

Martin R Prince  1 , Honglei Zhang, Jeffrey H Newhouse
Affiliations
Comment

Science to practice: a new insight into nephrotoxicity after contrast medium administration

Martin R Prince et al. Radiology. 2012 Dec.

Abstract

Liu et al (1) have shown that iodinated contrast medium preferentially vasoconstricts the glomerular afferent arterioles by depleting endothelial nitric oxide bioavailability. This potentiates an exaggerated afferent arteriolar vasoconstricting response to angiotensin II and opens possibilities for new methods to prevent or treat nephrotoxicity after contrast medium administration.

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