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Review
. 2013 Feb;60(1):49-74.
doi: 10.1016/j.pcl.2012.10.002.

Human milk composition: nutrients and bioactive factors

Olivia Ballard  1 , Ardythe L Morrow
Affiliations
Review

Human milk composition: nutrients and bioactive factors

Olivia Ballard et al. Pediatr Clin North Am. 2013 Feb.

Abstract

This article provides an overview of the composition of human milk, its variation, and its clinical relevance. The composition of human milk is the biological norm for infant nutrition. Human milk also contains many hundreds to thousands of distinct bioactive molecules that protect against infection and inflammation and contribute to immune maturation, organ development, and healthy microbial colonization. Some of these molecules (eg, lactoferrin) are being investigated as novel therapeutic agents. Human milk changes in composition from colostrum to late lactation, within feeds, by gestational age, diurnally, and between mothers. Feeding infants with expressed human milk is increasing.

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Figures

Figure 1
Figure 1
Milk protein concentrations, comparing milk from mothers who delivered preterm and term, by gestational age at delivery and weeks postpartum (adapted from Bauer & Gerss, 2011).
See this image and copyright information in PMC

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