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. 2013 Jan;26(1):1-6.
doi: 10.1016/j.yebeh.2012.10.010. Epub 2012 Nov 23.

Generic antiepileptic drug prescribing: a cross-sectional study

Jennifer Meyer  1 , David Fardo, Steven T Fleming, Claudia Hopenhayn, Yevgeniya Gokun, Melody Ryan
Affiliations

Generic antiepileptic drug prescribing: a cross-sectional study

Jennifer Meyer et al. Epilepsy Behav. 2013 Jan.

Abstract

The use of generic antiepileptic drugs (AEDs) in patients with epilepsy is controversial. The purpose of this study is to identify patient characteristics associated with increased odds of receiving a generic AED product. A large commercial database was used to identify patients with a primary diagnosis of epilepsy who were prescribed an AED during a three-month window. Data analysis found that those ≥65 years old had 15.7% greater odds of receiving a generic AED (OR = 1.157; 95% CI = 1.056-1.268). Patients with Medicaid were found to have 2.44 times the odds of having had a generic AED prescription (OR = 2.44; CI = 2.168-2.754). Patients residing in the Northeast had 12.6% decreased odds of receiving a generic AED (OR = 0.874; C I= 0.821-0.931). These patient characteristics could signify certain health care disparities and may represent potential confounders to future observational studies.

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Figures

Fig. 1
Fig. 1
Map of the United States divided into South, Northeast, Midwest, West and Pacific regions [25].
Fig. 2
Fig. 2
Distribution of antiepileptic prescriptions by brand and generic formulation*. *Those AEDs comprising less than 1% of the collective prescriptions were not included on the graph.
See this image and copyright information in PMC

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