Neurophysiological mechanisms underlying affiliative social behavior: insights from comparative research

Abstract

Humans are intensely social animals, and healthy social relationships are vital for proper mental health (see Lim and Young, 2006). By using animal models, the behavior, mental, and physiological processes of humans can be understood at a level that cannot be attained by studying human behavior and the human brain alone. The goals of this review are threefold. First, we define affiliative social behavior and describe the primary relationship types in which affiliative relationships are most readily observed--the mother-infant bond and pair-bonding. Second, we summarize neurophysiological studies that have investigated the role of neurohypophyseal nanopeptides (oxytocin and vasopressin) and the catecholamine dopamine in regulating affiliative social behavior and the implications of said research for our understanding of human social behavior. Finally, we discuss the merits and limitations of the using a comparative approach to enhance our understanding of the mechanisms underlying human affiliative social behavior.