Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2012 Nov 27:2012:bcr2012007275.
doi: 10.1136/bcr-2012-007275.

Malaria and the heart

Affiliations
Case Reports

Malaria and the heart

Smitha Bhat et al. BMJ Case Rep. .

Abstract

A 40-year-old healthy manual labourer from a malaria endemic area with no known risk factors for atherosclerotic coronary vascular disease was admitted to our hospital with a history of fever with chills and rigours. Physical examination revealed tachypnoea and icterus. Peripheral smear showed trophozoites of Plasmodium vivax and thrombocytopaenia. The patient was administered artesunate. Six hours after admission, he complained of severe substernal chest pain. A 12-lead ECG revealed ST elevations in leads I, II and aVL. Troponin T and creatine kinase MB were elevated and the random blood sugar was 49 mg%. Echocardiogram revealed left ventricle lateral wall hypokinesia. Hypoglycaemia was corrected. A provisional diagnosis of acute coronary syndrome as a complication of malaria or its treatment was made. He was treated with low molecular weight heparin and nitrates. The patient improved symptomatically. A repeat ECG was normal.

PubMed Disclaimer

Figures

Figure 1
Figure 1
ECG showing ST elevation in leads I and II.
Figure 2
Figure 2
ECG showing ST elevation in lead aVL.
Figure 3
Figure 3
ECG showing reversion of ST elevation in lead I.
Figure 4
Figure 4
ECG showing reversion of ST elevation in Lead II.
Figure 5
Figure 5
Peripheral smear showing Plasmodium vivax and thrombocytopaenia.
Figure 6
Figure 6
Peripheral smear showing Plasmodium vivax and thrombocytopaenia.

Similar articles

Cited by

References

    1. White NJ, Breman JG. Malaria. In: Fauci, Kasper, Hauser, Jameson, Loscalzo Longo Harrison's principles of internal medicine. New York, USA: McGraw Hill, 2012.
    1. Kochar DK. Severe Plasmodium vivax malaria: a report on serial cases from Bikaner in northwestern India. Am J Trop Med Hyg 2009;80:194–8. - PubMed
    1. Franzen D, Curtius JM, Heitz W, et al. Cardiac involvement during and after malaria. Clin Invest 1992;70:670–3. - PubMed
    1. Bethell DB, Phuong PT, Phuong CX, et al. Electrocardiographic monitoring in severe falciparum malaria. Trans R Soc Trop Med Hyg 1996;90:266–9. - PubMed
    1. Nieman AE, de Mast Q, Roestenberg M, et al. Cardiac complication after experimental human malaria infection: a case report. Malar J 2009;8:277. - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources