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Case Reports
. 2012 Sep;3(3):187-9.
doi: 10.4103/2229-5178.101815.

Wells syndrome

Affiliations
Case Reports

Wells syndrome

Manish Bansal et al. Indian Dermatol Online J. 2012 Sep.

Abstract

Wells syndrome or eosinophilic cellulitis is characterized clinically by an acute dermatitis resembling cellulitis and histopathologically by dermal eosinophilic infiltration. Various morphological presentations have been described. We report a 32-year-old female with recurrent, erythematous plaques on left forearm of 8 months duration, associated with mild itching that resolved leaving mild hyperpigmentation.

Keywords: Cellulitis; Wells syndrome; eosinophils.

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Conflict of interest statement

Conflict of Interest: No.

Figures

Figure 1
Figure 1
Clinical photograph showing erythematous and indurated plaque on the flexor aspect of left forearm below elbow (encircled)
Figure 2
Figure 2
Photomicrograph showing moderately dense superficial and deep perivascular and periappendageal infiltrate of eosinophils and lymphocytes (arrows) (H and E, ×100)
Figure 3
Figure 3
Photomicrograph showing eosinophils scattered in the interstitium of reticular dermis and around the deep vascular plexus (arrow) (H and E, ×400)

References

    1. Wells GC. Recurrent granulomatous dermatitis with eosinophilia. Trans St Johns Hosp Dermatol Soc. 1971;57:46–56. - PubMed
    1. Wells GC, Smith NP. Eosinophilic cellulitis. Br J Dermatol. 1979;100:101–9. - PubMed
    1. Aberer W, Konrad K, Wolff K. Wells’ syndrome is a distinctive disease entity and not a histologic diagnosis. J Am Acad Dermatol. 1988;18(1 Pt 1):105–14. - PubMed
    1. Schorr WF, Tauscheck AL, Dickson KB, Melski JW. Eosinophilic cellulitis (Wells’ syndrome): Histologic and clinical features in arthropod bite reactions. J Am Acad Dermatol. 1984;11:1043–9. - PubMed
    1. Wood C, Miller AC, Jacobs A, Hart R, Nickoloff BJ. Eosinophilic infiltration with flame figures. A distinctive tissue reaction seen in Wells’ syndrome and other diseases. Am J Dermatopathol. 1986;8:186–93. - PubMed

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