Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2012 Sep;3(3):193-5.
doi: 10.4103/2229-5178.101818.

Pemphigus vegetans: An unusual presentation

Ashish Dhamija  1 , Paschal D'souza, Ashok Meherda, Raj K Kothiwala
Affiliations
Case Reports

Pemphigus vegetans: An unusual presentation

Ashish Dhamija et al. Indian Dermatol Online J. 2012 Sep.

Abstract

Pemphigus vegetans is a rare variant of pemphigus vulgaris that is characterized by vegetating lesions primarily in the flexures. We report a 45-year-old male patient with an unusual presentation of the disease. A careful analysis of the clinical and laboratory findings enabled us to reach a diagnosis and successfully treat the patient.

Keywords: Diagnosis; pemphigus vegetans; treatment; unusual presentation.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: No.

Figures

Figure 1
Figure 1
Clinical photograph showing well-defined, irregular, hypertrophic, fissured plaque with oozing and crusting surrounding the mouth, extending above into the ala nasii
Figure 2
Figure 2
Histopathologic photograph showing the presence of microabscesses containing eosinophils and an intraepidermal cleft
Figure 3
Figure 3
High-power view of Figure 3
Figure 4
Figure 4
Clinical photograph showing dramatic response with significant clearing of the patient's lesions after treatment
Figure 5
Figure 5
Immunoperoxidase staining of lower part of epidermis (intercellular area)
See this image and copyright information in PMC

References

    1. Pasricha JS, Khaitan BK, Raman RS, Chandra M. Dexamethasone-cyclophosphamide pulse therapy for pemphigus. Int J Dermatol. 1995;34:875–82. - PubMed
    1. Lever W. Springfield: Thomas; 1965. Pemphigus and pemphigoid.
    1. Leroy D, Lebrun J, Maillard V, Mandard JC, Deschamps P. Pemphigus vegetant a type clinique de dermatite pustuleuse chronique de hallopeau. Ann Dermatol Venereol. 1982;109:549–55. - PubMed
    1. Torok L, Husz S, Ocsal H, Krischner A, Kiss M. Pemphigus vegetans presenting as acrodermatitis continua suppurativa. Eur J Dermatol. 2003;13:579–81. - PubMed
    1. Ahmed AR, Blose DA. Pemphigus vegetans.Neumann type and hallopeau type. Int J Dermatol. 1984;23:135–41. - PubMed

Publication types