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Randomized Controlled Trial
. 2013 Apr;44(4):407-16.
doi: 10.1016/j.jsat.2012.10.001. Epub 2012 Nov 26.

Preconceptional motivational interviewing interventions to reduce alcohol-exposed pregnancy risk

Karen S Ingersoll  1 , Sherry D Ceperich, Jennifer E Hettema, Leah Farrell-Carnahan, J Kim Penberthy
Affiliations
Randomized Controlled Trial

Preconceptional motivational interviewing interventions to reduce alcohol-exposed pregnancy risk

Karen S Ingersoll et al. J Subst Abuse Treat. 2013 Apr.

Abstract

Alcohol exposed pregnancy (AEP) is a leading cause of preventable birth defects. While randomized controlled trials (RCTs) have shown that multi-session motivational interviewing-based interventions reduce AEP risk, a one-session intervention could facilitate broader implementation. The purposes of this study were to: (1) test a one-session motivational AEP prevention intervention for community women and (2) compare outcomes to previous RCTs. Participants at risk for AEP (N=217) were randomized to motivational interviewing+assessment feedback (EARLY), informational video, or informational brochure conditions. Outcomes were drinks per drinking day (DDD), ineffective contraception rate, and AEP risk at 3 and 6 months. All interventions were associated with decreased DDD, ineffective contraception rate, and AEP risk. Participants who received EARLY had larger absolute risk reductions in ineffective contraception and AEP risk, but not DDD. Effect sizes were compared to previous RCTs. The one-session EARLY intervention had less powerful effects than multi-session AEP prevention interventions among community women, but may provide a new option in a continuum of preventive care.

Trial registration: ClinicalTrials.gov NCT01446653.

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Conflict of interest statement

Conflict of interest statement: Dr. Hettema sells a motivational interviewing training video. No other financial disclosures or conflicts were reported by the authors of this paper.

Figures

Fig. 1
Fig. 1
Study Flowchart.
See this image and copyright information in PMC

References

    1. Abel EL. Fetal alcohol syndrome. Oradell, NJ: Medical Economics Co; 1990.
    1. Agrawal A, Grant JD, Littlefield A, Waldron M, Pergadia ML, Lynskey MT, Heath AC. Developing a quantitative measure of alcohol consumption for genomic studies on prospective cohorts. Journal of Studies on Alcohol and Drugs. 2009;70:157–168. - PMC - PubMed
    1. Borenstein M, Hedges LV, Higgins JPT, Rothstein H. Comprehensive meta-analysis, version 2. 2. Englewood, NJ: Biostat, Inc; 2005.
    1. Bower P, Gilbody S. Stepped care in psychological therapies: Access, effectiveness and efficiency. narrative literature review. The British Journal of Psychiatry: The Journal of Mental Science. 2005;186:11–17. - PubMed
    1. Centers for Disease Control and Prevention. Alcohol use in pregnancy. 2009 Retrieved 02/22, 2010, from http://www.cdc.gov/ncbddd/fasd/alcohol-use.html.

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