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. 2013 Feb;205(2):209-12.
doi: 10.1016/j.amjsurg.2012.05.031. Epub 2012 Nov 27.

The use of porcine acellular dermal matrix in a bridge technique for complex abdominal wall reconstruction: an outcome analysis

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The use of porcine acellular dermal matrix in a bridge technique for complex abdominal wall reconstruction: an outcome analysis

Ketan M Patel et al. Am J Surg. 2013 Feb.

Abstract

Background: Outcomes using the porcine acellular dermal matrix (PADM) in abdominal wall reconstruction (AWR) have been reported when used for midline reinforcement; however, there have been no reports focused on outcomes when used as a bridging mesh.

Methods: A retrospective review was conducted of all patients who underwent AWR with a non-cross-linked PADM as a bridged repair without midline fascial approximation.

Results: Nine patients were identified with an average follow-up of 546 days. The average preoperative hernia defect diameter was 22.4 cm. After PADM placement, the average defect diameter was 9.8 cm. Complications occurred in 55.6% of patients, with PADM exposure occurring in all of these patients. No PADM was explanted, and all patients eventually healed. Abdominal wall eventration and/or recurrence occurred in 8 of 9 (88.9%) patients.

Conclusions: When fascial approximation cannot be achieved, PADM bridging may be the best option to avoid complications associated with synthetic mesh. However, there is a high potential for abdominal wall eventration and/or recurrence.

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