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. 2013 Mar;162(3):637-9.
doi: 10.1016/j.jpeds.2012.10.043. Epub 2012 Nov 27.

Incidence and characteristics of pseudoprecocious puberty because of severe primary hypothyroidism

Susanne M Cabrera  1 , Linda A DiMeglio, Erica A Eugster
Affiliations

Incidence and characteristics of pseudoprecocious puberty because of severe primary hypothyroidism

Susanne M Cabrera et al. J Pediatr. 2013 Mar.

Abstract

Severe primary hypothyroidism is a presumed rare cause of pseudoprecocious puberty (PsPP). Here, we report a 24% incidence of PsPP among 33 children with profound hypothyroidism. Those with PsPP were older and trended toward a higher thyroid stimulating hormone. Increased awareness of PsPP can hasten diagnosis and appropriate treatment.

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Figures

Figure
Figure
A, Comparison of CA and TSH at presentation in children with (gray) and without (white) PsPP. B, Comparison of height-SDS (ht-SDS), weight-SDS (wt-SDS), BMI-SDS, and BA-SDS at presentation in children with (gray) and without (white) PsPP. Data is shown as box-and-whiskers plot.
See this image and copyright information in PMC

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