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. 1978 Jan 7;1(6104):14-6.
doi: 10.1136/bmj.1.6104.14.

Antinuclear antibodies in patients receiving non-practolol beta-blockers

J D Wilson, J Y Bullock, D C Sutherland, C Main, K P O'Brien

Antinuclear antibodies in patients receiving non-practolol beta-blockers

J D Wilson et al. Br Med J. .

Abstract

Antinuclear antibodies (ANA) were found in 54 (7.0%) out of 767 treated hypertensive patients compared with 59 (2.4%) out of 2470 healthy controls. Inclusion of a non-practolol beta-blocker in the treatment regimen did not significantly affect the incidence of ANA. ANA was found in significantly more patients being treated with methyldopa (13.0%) than patients receiving other hypotensive agents (3.8%). Non-practolol beta-blockers in combination with methyldopa did not increase the incidence of ANA further.

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