Inflammasome: Turning on and off NLRP3

Comment

Olive Leavy. Nat Rev Immunol. 2013 Jan.

. 2013 Jan;13(1):1.

doi: 10.1038/nri3366. Epub 2012 Nov 30.

No abstract available

Comment on

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.
Lee GS, Subramanian N, Kim AI, Aksentijevich I, Goldbach-Mansky R, Sacks DB, Germain RN, Kastner DL, Chae JJ. Lee GS, et al. Nature. 2012 Dec 6;492(7427):123-7. doi: 10.1038/nature11588. Epub 2012 Nov 11. Nature. 2012. PMID: 23143333 Free PMC article.
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β.
Mishra BB, Rathinam VA, Martens GW, Martinot AJ, Kornfeld H, Fitzgerald KA, Sassetti CM. Mishra BB, et al. Nat Immunol. 2013 Jan;14(1):52-60. doi: 10.1038/ni.2474. Epub 2012 Nov 18. Nat Immunol. 2013. PMID: 23160153 Free PMC article.