Comment on

• Dangers within: DAMP responses to damage and cell death in kidney disease.

  Rosin DL, Okusa MD. Rosin DL, et al. J Am Soc Nephrol. 2011 Mar;22(3):416-25. doi: 10.1681/ASN.2010040430. Epub 2011 Feb 18. J Am Soc Nephrol. 2011. PMID: 21335516 Free PMC article. Review.
• Emerging role of innate immunity in organ transplantation: part I: evolution of innate immunity and oxidative allograft injury.

  Land WG. Land WG. Transplant Rev (Orlando). 2012 Apr;26(2):60-72. doi: 10.1016/j.trre.2011.05.001. Epub 2011 Oct 13. Transplant Rev (Orlando). 2012. PMID: 22000662 Review.
• F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells.

  Ahrens S, Zelenay S, Sancho D, Hanč P, Kjær S, Feest C, Fletcher G, Durkin C, Postigo A, Skehel M, Batista F, Thompson B, Way M, Reis e Sousa C, Schulz O. Ahrens S, et al. Immunity. 2012 Apr 20;36(4):635-45. doi: 10.1016/j.immuni.2012.03.008. Epub 2012 Apr 5. Immunity. 2012. PMID: 22483800
• The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.

  Zhang JG, Czabotar PE, Policheni AN, Caminschi I, Wan SS, Kitsoulis S, Tullett KM, Robin AY, Brammananth R, van Delft MF, Lu J, O'Reilly LA, Josefsson EC, Kile BT, Chin WJ, Mintern JD, Olshina MA, Wong W, Baum J, Wright MD, Huang DC, Mohandas N, Coppel RL, Colman PM, Nicola NA, Shortman K, Lahoud MH. Zhang JG, et al. Immunity. 2012 Apr 20;36(4):646-57. doi: 10.1016/j.immuni.2012.03.009. Epub 2012 Apr 5. Immunity. 2012. PMID: 22483802
• Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.

  Oka T, Hikoso S, Yamaguchi O, Taneike M, Takeda T, Tamai T, Oyabu J, Murakawa T, Nakayama H, Nishida K, Akira S, Yamamoto A, Komuro I, Otsu K. Oka T, et al. Nature. 2012 May 10;485(7397):251-5. doi: 10.1038/nature10992. Nature. 2012. PMID: 22535248 Free PMC article.