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Case Reports
. 2013 Sep;7(5):634-6.
doi: 10.1111/irv.12059. Epub 2012 Nov 30.

Fatal respiratory distress syndrome due to coronavirus infection in a child with severe combined immunodeficiency

Aleksandra Szczawinska-Poplonyk  1 , Katarzyna Jonczyk-Potoczna, Anna Breborowicz, Alicja Bartkowska-Sniatkowska, Magdalena Figlerowicz
Affiliations
Case Reports

Fatal respiratory distress syndrome due to coronavirus infection in a child with severe combined immunodeficiency

Aleksandra Szczawinska-Poplonyk et al. Influenza Other Respir Viruses. 2013 Sep.

Abstract

Coronaviruses have been demonstrated to contribute substantially to respiratory tract infections among the child population. Though infected children commonly present mild upper airway symptoms, in high-risk patients with underlying conditions, particularly in immunocompromised children these pathogens may lead to severe lung infection and extrapulmonary disorders. In this paper, we provide the first report of the case of a 15-month-old child with severe combined immunodeficiency and coronavirus HKU1-related pneumonia with fatal respiratory distress syndrome.

Keywords: Coronavirus; children; pneumonia; severe combined immunodeficiency.

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Figures

Figure 1
Figure 1
The chest X‐ray of a 15‐month‐old child with severe combined immunodeficiency and respiratory distress syndrome due to coronavirus HKU1 infection. Note the massive alveolar and interstitial infiltrations, with bilaterally decreased aeration of the lung fields and blurred borders of the diaphragm and the heart shape.
See this image and copyright information in PMC

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