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Comment
. 2013 Jan;15(1):83-4.
doi: 10.1038/aja.2012.133. Epub 2012 Dec 3.

Identification, characterization and targeting of Docetaxel-resistant prostate cancer cells

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Comment

Identification, characterization and targeting of Docetaxel-resistant prostate cancer cells

Tanya I Stoyanova et al. Asian J Androl. 2013 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Isolation and characterization of Docetaxel-resistant prostate cancer cells. (a) Cells preferentially surviving Docetaxel treatment express low levels of pan-HLAI-antigens and CK and high levels of active Notch and Hedgehog signaling. (b) Prostate cancer cells with a Docetaxel-resistant phenotype can serve as tumor initiating cells. (c) Docetaxel-resistant prostate cancer cells are dependent on Notch and Hedgehog signaling. CK, cytokeratins.

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