Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2012 Dec;63(12):1234-8.
doi: 10.1176/appi.ps.201100528.

Life Goals Collaborative Care for patients with bipolar disorder and cardiovascular disease risk

Amy M Kilbourne  1 , David E Goodrich, Zongshan Lai, Julia Clogston, Jeanette Waxmonsky, Mark S Bauer
Affiliations
Randomized Controlled Trial

Life Goals Collaborative Care for patients with bipolar disorder and cardiovascular disease risk

Amy M Kilbourne et al. Psychiatr Serv. 2012 Dec.

Abstract

Objective: This pilot study compared Life Goals Collaborative Care (LGCC) with enhanced treatment as usual in reducing cardiometabolic risk factors and improving outcomes for persons with bipolar disorder.

Methods: Participants were randomly assigned to LGCC (N=34) or enhanced treatment as usual (N=34). LGCC included four weekly self-management sessions and monthly telephone contacts for six months thereafter. Enhanced treatment as usual included wellness mailings. Outcomes were blood pressure, body mass index (BMI), quality of life, functioning, and symptoms.

Results: Compared with enhanced treatment as usual, LGCC was not associated with reductions in cardiometabolic risk factors in 12-month repeated-measures analyses. Among patients with a BMI of ≥30 or systolic blood pressure of ≥140, LGCC was associated with improvements in functioning (beta=-2.2 and beta=-3.8, respectively, p=.04) and reduced depressive symptoms (beta=-2.0 and -3.5, respectively, p=.04).

Conclusions: Further research is needed to determine whether LGCC improves outcomes for patients with elevated cardiometabolic risk.

PubMed Disclaimer

References

    1. Kilbourne AM, Morden NE, Austin K, et al. Excess heart-disease-related mortality in a national study of patients with mental disorders: identifying modifiable risk factors. General Hospital Psychiatry. 2009;31:555–563. - PMC - PubMed
    1. Katon WJ. Clinical and health services relationships between major depression, depressive symptoms, and general medical illness. Biological Psychiatry. 2003;54:216–226. - PubMed
    1. Bryant-Comstock L, Stender M, Devercelli G. Health care utilization and costs among privately insured patients with bipolar I disorder. Bipolar Disorders. 2002;4:398–405. - PubMed
    1. Judd LL, Akiskal HS. The prevalence and disability of bipolar spectrum disorders in the US population: re-analysis of the ECA database taking into account subthreshold cases. Journal of Affective Disorders. 2003;73:123–131. - PubMed
    1. Wildes JE, Marcus MD, Fagiolini A. Obesity in patients with bipolar disorder: a biopsychosocial-behavioral model. Journal of Clinical Psychiatry. 2006;67:904–915. - PubMed

Publication types