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. 2011 Dec;2(4):291-7.
doi: 10.1007/s13193-012-0125-7. Epub 2012 Jan 31.

Multimodality management of extremity soft tissue sarcomas-an Indian perspective

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Multimodality management of extremity soft tissue sarcomas-an Indian perspective

Ajay Puri et al. Indian J Surg Oncol. 2011 Dec.

Abstract

Soft-tissue sarcomas are a rare and heterogeneous group of tumors. The last few decades have seen rapid strides in the management of these complex lesions. The presence of a soft-tissue sarcoma in the extremity is no longer an indication for amputation. Function preserving alternatives for local control in these lesions are the norm without compromising on overall disease survival. Good functional and oncological results can be achieved with a combination of excision of the tumor and where required, suitable adjuvant therapies. These lesions are best managed at specialty centres where the requisite multidisciplinary care can be offered to the patient to optimise results. This article outlines the current understanding and emphasises the multimodality management of these challenging tumors. We also present Indian data of the incidence and oncologic outcomes of these lesions and suggest a treatment algorithm.

Keywords: Multimodality; Tumor.

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Figures

Fig. 1
Fig. 1
Age distribution of soft tissue sarcomas
Fig. 2
Fig. 2
Kaplan Meier curve showing disease free survival
Fig. 3
Fig. 3
Kaplan Meier curve showing overall survival
Fig. 4
Fig. 4
Treatment algorithm for non metastatic extremity sarcomas

References

    1. Kasper B, Gil T, D’Hondt V, Gebhart M, Awada A. Novel treatment strategies for soft tissue sarcoma. Crit Rev Oncol Hematol. 2007;62:9–15. doi: 10.1016/j.critrevonc.2006.11.008. - DOI - PubMed
    1. Jansen-Landheer ML, Krijnen P, Oostindier MJ, Kloosterman-Boele WM, Noordijk EM, Nooij MA, et al. Improved diagnosis and treatment of soft tissue sarcoma patients after implementation of national guidelines: a population-based study. Eur J Surg Oncol. 2009;35:1326–1332. doi: 10.1016/j.ejso.2009.05.002. - DOI - PubMed
    1. Grimer R, Judson I, Peake D, Seddon B (2010) Guidelines for the management of soft tissue sarcomas. Sarcoma 506182 - PMC - PubMed
    1. National Cancer Institute: Adult Soft Tissue Sarcoma Treatment (PDQ®) (2011) Available from: http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarco... [updated on 24 Jan 2011]
    1. Narvani AA, Tsiridis E, Saifuddin A, Briggs T, Cannon S. Does image guidance improve accuracy of core needle biopsy in diagnosis of soft tissue tumours? Acta Orthop Belg. 2009;75:239–244. - PubMed

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