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. 2011 Dec;2(4):302-8.
doi: 10.1007/s13193-012-0134-6. Epub 2012 Apr 3.

Curent concepts in pathology of soft tissue sarcoma

Nuzhat Husain  1 , Nidhi Verma
Affiliations

Curent concepts in pathology of soft tissue sarcoma

Nuzhat Husain et al. Indian J Surg Oncol. 2011 Dec.

Abstract

Soft tissue sarcomas (STS) constitute a heterogeneous category of soft tissue neoplasia composed mostly of uncommon tumors of diverse histology, different biology and varied outcomes. Substantial developments in immunohistochemistry (IHC), cytogenetics and molecular genetics of STS have caused a significant change in the classification and diagnosis of these tumors with a direct implication for clinical management and prognosis. In this review we discuss newer developments impacting diagnosis and prediction.

Keywords: Grading; Immunohistochemistry; Molecular; Pathology; Sarcoma; Soft tissue.

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Figures

Fig. 1
Fig. 1
a. Vascular network highlighted in CD 34 stain in a sclerosing epithelioid fibrosarcoma b. Dermatofibrosarcoma protuberans showing diffuse CD 34 expression c. Diffuse desmin expression in a pleomorphic rhabdomyosarcoma, d. HMB 45 in amelanotic melanoma, e. Diffuse CD117 in GIST and f. Focal SMA in GIST
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