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. 2011 Dec;20(4):235-42.
doi: 10.1055/s-0031-1295521.

Treatment of Iatrogenic Pseudoaneurysms Using Ultrasound-Guided Thrombin Injection over a 5-Year Period

Affiliations

Treatment of Iatrogenic Pseudoaneurysms Using Ultrasound-Guided Thrombin Injection over a 5-Year Period

Kaushal J Shah et al. Int J Angiol. 2011 Dec.

Abstract

In this study we demonstrate that ultrasound (US)-guided injection of thrombin is a safe and effective way to treat iatrogenic pseudoaneurysms as a new treatment modality at a 650-bed urban community hospital. We included retrospective chart review of patients who were treated for iatrogenic pseudoaneurysms from January 2004 to June 2010 at a single institution. All patients' pseudoaneurysms were treated using US-guided thrombin injection. This study demonstrated an overall success rate of 97.1% in treating iatrogenic pseudoaneurysms in 33 of 34 patients. One patient underwent open surgical repair. No mortality or complications were noted. The study was successful in demonstrating that the US-guided injection of thrombin is an efficacious way to treat iatrogenic pseudoaneurysms and can be safely implemented as a new treatment modality by appropriately trained vascular surgeons. A review of different techniques is included. An algorithm for the treatment of iatrogenic pseudoaneurysms is proposed from this study.

Keywords: Pseudoaneurysm; false aneurysm; ultrasound-guided thrombin injection.

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Figures

Figure 1
Figure 1
Histogram of age versus pseudoaneurysm frequency.
Figure 2
Figure 2
Histogram of pseudoaneurysm dimensions by frequency.
Figure 3
Figure 3
Histogram of thrombin amount used on pseudoaneurysm patients.
Figure 4
Figure 4
Algorithm for treatment of pseudoaneurysms.

References

    1. Franz R W, Hughart C. Delayed pseudoaneurysm repair: a case report. Int J Angiol. 2007;16(3):119–120. - PMC - PubMed
    1. Franklin J A, Brigham D, Bogey W M, Powell C S. Treatment of iatrogenic false aneurysms. J Am Coll Surg. 2003;197(2):293–301. - PubMed
    1. Kang S S, Labropoulos N, Mansour M A, et al. Expanded indications for ultrasound-guided thrombin injection of pseudoaneurysms. J Vasc Surg. 2000;31(2):289–298. - PubMed
    1. Khoury M, Rebecca A, Greene K, et al. Duplex scanning-guided thrombin injection for the treatment of iatrogenic pseudoaneurysms. J Vasc Surg. 2002;35(3):517–521. - PubMed
    1. Kang S S, Labropoulos N, Mansour M A, Baker W H. Percutaneous ultrasound guided thrombin injection: a new method for treating postcatheterization femoral pseudoaneurysms. J Vasc Surg. 1998;27(6):1032–1038. - PubMed