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Comparative Study
. 2012 Dec 3:7:168.
doi: 10.1186/1746-1596-7-168.

Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

Esam G Abdelrahman  1 , Gasim I Gasim, Imad R Musa, Leana M Elbashir, Ishag Adam
Affiliations
Comparative Study

Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

Esam G Abdelrahman et al. Diagn Pathol. .

Abstract

Background: Iron deficiency anemia (IDA) is a major health problem during pregnancy and it has adverse effects on the mother and the newborn. Red cell distribution width (RDW), which is a quantitative measure for red cell size variation (anisocytosis), is a predictor of IDA. Little is known regarding RDW and IDA during pregnancy.

Methods: A cross sectional study was conducted at the antenatal clinic of Khartoum Hospital, Sudan, to determine the performance of RDW in the diagnosis of IDA using serum ferritin as a gold standard.

Results: Among 194 pregnant women with a gestational period of 21.4 ± 6.5 weeks, 57 (29.4%) had IDA according to serum ferritin levels (<15 μg/l) and 61 (31.4%) had IDA according to RDW (>14.5). The sensitivity, specificity, positive predictive value, and negative predictive value of RDW where serum ferritin was the gold standard were 43.8% (95% CI: 31.4-57.0%), 73.7% (95% CI: 65.8-80.5%), 41.0% (95% CI: 29.2-53.6%), and 76.0% (95% CI: 68.1-82.6%), respectively.

Conclusions: In this study, we found that RDW has a poor performance in diagnosing IDA among pregnant women compared with serum ferritin as the gold standard.

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Figures

Figure 1
Figure 1
Peripheral blood film with changes attributed to iron deficiency anemia.
See this image and copyright information in PMC

References

    1. World Health Organization. Worldwide prevalence of anaemia, WHO vitamin and mineral nutrition information system 1993 – information system 2005. Geneva: World Health Organization; Available at: http://whqlibdoc.who.int/publications/2008/9789241596657_eng.pdf. - PubMed
    1. Mohammed AA, Elnour MH, Mohammed EE, Ahmed SA, Abdelfattah AI. Maternal mortality in Kassala State - Eastern Sudan: community-based study using reproductive age mortality survey (RAMOS) BMC Pregnancy Childbirth. 2011;11:102. doi: 10.1186/1471-2393-11-102. - DOI - PMC - PubMed
    1. Adam I, Elhassan EM, Haggaz AE, Ali AA, Adam GK. A: perspective of the epidemiology of malaria and anemia and their impact on maternal and perinatal outcomes in Sudan. J Infect Dev Ctries. 2011;5(2):83–87. - PubMed
    1. De Benoist B, McLean E, Egli I, Cogswell M. Worldwide Prevalence of anemia 1993 2005: WHO Global Database on Anemia. Geneva: World Health Organization; 2008.
    1. Allen LH. Anemia and iron deficiency: effects on pregnancy outcome. Am J Clin Nutr. 2000;71:1280S–1284S. - PubMed

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