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. 2013 Feb:72:133-6.
doi: 10.1016/j.apradiso.2012.10.011. Epub 2012 Oct 23.

A niobium water target for routine production of [¹⁸F]Fluoride with a MC 17 cyclotron

J Siikanen  1 , T Ohlsson, J Medema, J Van-Essen, A Sandell
Affiliations

A niobium water target for routine production of [¹⁸F]Fluoride with a MC 17 cyclotron

J Siikanen et al. Appl Radiat Isot. 2013 Feb.

Abstract

A [(18)F]Fluoride water target was constructed for a Scanditronix MC 17 cyclotron, without a beam line, with a typical wide beam of ∼30 × 5 mm(2). Niobium was used as target chamber material. One hour irradiation with 45μA protons yields about 110 GBq [(18)F]Fluoride. The saturation yield is 8.0 ± 0.6 GBq/μA (EOB). The FDG yield is 60 ± 5% (EOS) with a TracerLab MX (G.E. Healthcare). More than 100 GBq FDG is routinely produced after a 2h irradiation.

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