The cyclic AMP pathway
- PMID: 23209152
- PMCID: PMC3504441
- DOI: 10.1101/cshperspect.a011148
The cyclic AMP pathway
Abstract
cAMP was the first second messenger to be identified. Its three main effectors are PKA (which phosphorylates numerous metabolic enzymes), EPAC (a guanine-nucleotide-exchange factor), and cyclic-nucleotide-gated ion channels.
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