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Case Reports
. 2012:2012:364735.
doi: 10.1155/2012/364735. Epub 2012 Mar 7.

Loss of renal allografts secondary to Candida vascular complications in two recipients from the same donor

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Case Reports

Loss of renal allografts secondary to Candida vascular complications in two recipients from the same donor

Govardhana Rao Yannam et al. Case Rep Transplant. 2012.

Abstract

Infections remain a major cause of morbidity and mortality in transplant patients. Organ recipients are also susceptible to donor-derived pathogens and the majority of donor infections are easily treatable. Rarely, some pathogens have produced life-threatening complications by compromising the vascular anastomosis. In this case series we report loss of two kidney allografts secondary to vascular complications due to Candida albicans. Both recipients received grafts from a common donor, in whom Candida bacteremia in the donor was not apparent at the time of organ acceptance but became apparent on delayed cultures.

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Figures

Figure 1
Figure 1
A possible pseudoaneurysm in the region of the vascular anastomosis revealed by Color Doppler Ultrasound (a) with an area of turbulent and to-and-fro waveforms. Follow-up MRI (b) confirmed a bilobed pseudoaneurysm (white arrow) and revealed a segment of high-grade stenosis of the right external iliac artery (red arrow). Conventional angiogram image (c) in AP view reconfirmed the pseudoaneurysm (white arrow) and a segment of high-grade stenosis of the right external iliac artery (red arrow) with stenosis of the transplanted renal artery (green arrow).
Figure 2
Figure 2
Pathological examination of explant revealed renal artery and intraparenchymal arterial branches positive for fungal organisms by GMS stain.

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References

    1. Rao YG, Mirza DF. Infections transmitted from donors to recipients following organ transplantation. National Medical Journal of India. 2005;18(4):189–194. - PubMed
    1. Battaglia M, Ditonno P, Fiore T, De Ceglie G, Regina G, Selvaggi FP. True mycotic arteritis by Candida albicans in 2 kidney transplant recipients from the same donor. Journal of Urology. 2000;163(4):1236–1237. - PubMed
    1. Garrido J, Lerma JL, Heras M, et al. Pseudoaneurysm of the iliac artery secondary to Aspergillus infection in two recipients of kidney transplants from the same donor. American Journal of Kidney Diseases. 2003;41(2):488–492. - PubMed
    1. Matignon M, Botterel F, Audard V, et al. Outcome of renal transplantation in eight patients with Candida sp. contamination of preservation fluid. American Journal of Transplantation. 2008;8(3):697–700. - PubMed
    1. Calviño J, Romero R, Pintos E, et al. Renal artery rupture secondary to pretransplantation Candida contamination of the graft in two different recipients. American Journal of Kidney Diseases. 1999;33(1):p. E3. - PubMed

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