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. 1979 Oct;32(1):234-9.
doi: 10.1128/JVI.32.1.234-239.1979.

Apparent posttranscriptional block to anaerobic induction of endogenous leukemia virus

P A Whitaker-Dowling, K R Marotti, G R Anderson

Apparent posttranscriptional block to anaerobic induction of endogenous leukemia virus

P A Whitaker-Dowling et al. J Virol. 1979 Oct.

Abstract

Uninfected Fischer rat cells were induced by anaerobic stress to transcribe high levels of endogenous type C leukemia virus RNA. Complete 35S virus RNA with attached polyadenylic acid sequences was found associated with polysomes, indicating functional mRNA. Since no mature virus was released under these conditions, the presence of a posttranscriptional block to complete virus synthesis is strongly indicated.

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References

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