UPS delivers pluripotency
- PMID: 23217415
- DOI: 10.1016/j.stem.2012.11.009
UPS delivers pluripotency
Abstract
In this issue of Cell Stem Cell, Buckley et al. (2012) show that the ubiquitin-proteasome system (UPS) regulates pluripotency in embryonic stem cells and induced pluripotent stem cells, opening the door to a better understanding at the system level of protein dynamics responsible for the maintenance and induction of pluripotency.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system.Cell Stem Cell. 2012 Dec 7;11(6):783-98. doi: 10.1016/j.stem.2012.09.011. Epub 2012 Oct 25. Cell Stem Cell. 2012. PMID: 23103054 Free PMC article.
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