Herpes simplex virus type-2 assay specificity and male circumcision to reduce herpes simplex virus type-2 acquisition
- PMID: 23221430
- PMCID: PMC3787836
- DOI: 10.1097/QAD.0b013e32835aa181
Herpes simplex virus type-2 assay specificity and male circumcision to reduce herpes simplex virus type-2 acquisition
Abstract
Three male circumcision (MC) trials which enrolled over 10,000 men of different ages, settings (urban vs. rural), countries (Uganda, Kenya and South Africa), and which utilized different surgical techniques were consistent in showing a 51–60% in reduction in HIV incidence [–5], and all three trials reported that MC decreased high-risk human papillomavirus (HR-HPV) prevalence by 32–35% [–8].
Comment in
-
Response to 'Herpes simplex virus type-2 (HSV-2) assay specificity and male circumcision to reduce HSV-2 acquisition.AIDS. 2013 Jan 2;27(1):149-50. doi: 10.1097/QAD.0b013e328358cc92. AIDS. 2013. PMID: 23221431 No abstract available.
Comment on
-
Circumcision status and incident herpes simplex virus type 2 infection, genital ulcer disease, and HIV infection.AIDS. 2012 Jun 1;26(9):1141-9. doi: 10.1097/QAD.0b013e328352d116. AIDS. 2012. PMID: 22382150 Free PMC article. Clinical Trial.
Similar articles
-
Response to 'Herpes simplex virus type-2 (HSV-2) assay specificity and male circumcision to reduce HSV-2 acquisition.AIDS. 2013 Jan 2;27(1):149-50. doi: 10.1097/QAD.0b013e328358cc92. AIDS. 2013. PMID: 23221431 No abstract available.
-
Circumcision status and incident herpes simplex virus type 2 infection, genital ulcer disease, and HIV infection.AIDS. 2012 Jun 1;26(9):1141-9. doi: 10.1097/QAD.0b013e328352d116. AIDS. 2012. PMID: 22382150 Free PMC article. Clinical Trial.
-
Effects of genital ulcer disease and herpes simplex virus type 2 on the efficacy of male circumcision for HIV prevention: Analyses from the Rakai trials.PLoS Med. 2009 Nov;6(11):e1000187. doi: 10.1371/journal.pmed.1000187. Epub 2009 Nov 24. PLoS Med. 2009. PMID: 19936044 Free PMC article. Clinical Trial.
-
Herpes simplex virus type 2: epidemiology and management options in developing countries.Sex Transm Infect. 2007 Feb;83(1):16-22. doi: 10.1136/sti.2006.020966. Epub 2006 Nov 10. Sex Transm Infect. 2007. PMID: 17098770 Free PMC article. Review.
-
Herpes simplex virus 2 infection: molecular association with HIV and novel microbicides to prevent disease.Med Microbiol Immunol. 2015 Apr;204(2):161-76. doi: 10.1007/s00430-014-0358-x. Epub 2014 Sep 11. Med Microbiol Immunol. 2015. PMID: 25209142 Free PMC article. Review.
Cited by
-
Medical male circumcision and herpes simplex virus 2 acquisition: posttrial surveillance in Kisumu, Kenya.J Infect Dis. 2013 Dec 1;208(11):1869-76. doi: 10.1093/infdis/jit371. Epub 2013 Jul 30. J Infect Dis. 2013. PMID: 23901089 Free PMC article. Clinical Trial.
-
No-flip ShangRing circumcision in 10-12 year old boys: Results from randomized clinical trials in Kenya.PLoS One. 2020 May 22;15(5):e0233150. doi: 10.1371/journal.pone.0233150. eCollection 2020. PLoS One. 2020. PMID: 32442198 Free PMC article. Clinical Trial.
-
Wound healing rates and wound problems of conventional circumcision compared with ring circumcision: A meta-analysis.Int Wound J. 2023 Nov;20(9):3699-3707. doi: 10.1111/iwj.14262. Epub 2023 Jun 11. Int Wound J. 2023. Retraction in: Int Wound J. 2025 Feb;22(2):e70204. doi: 10.1111/iwj.70204. PMID: 37303303 Free PMC article. Retracted.
-
Incidence of herpes simplex virus type 2 infections in Africa: a systematic review.Open Forum Infect Dis. 2014 Jul 11;1(2):ofu043. doi: 10.1093/ofid/ofu043. eCollection 2014 Sep. Open Forum Infect Dis. 2014. PMID: 25734115 Free PMC article. Review.
-
Prevalence and incidence estimation of HSV-2 by two IgG ELISA methods among South African women at high risk of HIV.PLoS One. 2015 Mar 23;10(3):e0120207. doi: 10.1371/journal.pone.0120207. eCollection 2015. PLoS One. 2015. PMID: 25799522 Free PMC article.
References
-
- Gray RH, Kigozi G, Serwadda D, Makumbi F, Watya S, Nalugoda F, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet. 2007;369:657–666. - PubMed
-
- Bailey RC, Moses S, Parker CB, Agot K, Maclean I, Krieger JN, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. 2007;369:643–656. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical