Herpes simplex virus type-2 assay specificity and male circumcision to reduce herpes simplex virus type-2 acquisition
- PMID: 23221430
 - PMCID: PMC3787836
 - DOI: 10.1097/QAD.0b013e32835aa181
 
Herpes simplex virus type-2 assay specificity and male circumcision to reduce herpes simplex virus type-2 acquisition
Abstract
Three male circumcision (MC) trials which enrolled over 10,000 men of different ages, settings (urban vs. rural), countries (Uganda, Kenya and South Africa), and which utilized different surgical techniques were consistent in showing a 51–60% in reduction in HIV incidence [–5], and all three trials reported that MC decreased high-risk human papillomavirus (HR-HPV) prevalence by 32–35% [–8].
Comment in
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  Response to 'Herpes simplex virus type-2 (HSV-2) assay specificity and male circumcision to reduce HSV-2 acquisition.AIDS. 2013 Jan 2;27(1):149-50. doi: 10.1097/QAD.0b013e328358cc92. AIDS. 2013. PMID: 23221431 No abstract available.
 
Comment on
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  Circumcision status and incident herpes simplex virus type 2 infection, genital ulcer disease, and HIV infection.AIDS. 2012 Jun 1;26(9):1141-9. doi: 10.1097/QAD.0b013e328352d116. AIDS. 2012. PMID: 22382150 Free PMC article. Clinical Trial.
 
References
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- Gray RH, Kigozi G, Serwadda D, Makumbi F, Watya S, Nalugoda F, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet. 2007;369:657–666. - PubMed
 
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- Bailey RC, Moses S, Parker CB, Agot K, Maclean I, Krieger JN, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. 2007;369:643–656. - PubMed
 
 
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