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Review
. 2013 Winter;53(1):79-90.
doi: 10.1097/IIO.0b013e3182773ab4.

Corneal collagen cross-linking for keratoconus and post-LASIK ectasia

Ronald N Gaster, Ana L Caiado Canedo, Yaron S Rabinowitz
Review

Corneal collagen cross-linking for keratoconus and post-LASIK ectasia

Ronald N Gaster et al. Int Ophthalmol Clin. 2013 Winter.
No abstract available

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Figures

Figure 1
Figure 1
Wollensak et al found that CXL produced a 328.9% increase in rigidity of the human cornea.
Figure 2
Figure 2
Keratocyte apoptosis occurs to a depth of 300 microns with 3 mW/cm2 of UV-A irradiance for 30 minutes.
Figure 3
Figure 3
Riboflavin acts as a shield to the UV-A irradiance and further protects the deeper structures of the eye. (Courtesy of Prof. E. Spoerl.)
See this image and copyright information in PMC

References

    1. Spoerl E, Huhle M, Seiler T. Induction of cross-links in corneal tissue. Exp Eye Res. 1998;66:97–103. - PubMed
    1. Spoerl E, Seiler T. Techniques for stiffening the cornea. J Refract Surg. 1999;15:711–713. - PubMed
    1. Wollensak G, Spoerl E, Seiler T. Stress-strain measurements of human and porcine cornea after riboflavin/ultraviolet-A-induced crosslinking. J Refract Surg. 2003;29:1780–1785. - PubMed
    1. Spoerl E, Wollensak G, Seiler T. Increased resistance of crosslinked cornea against enzymatic digestion. Curr Eye Res. 2004;29:35–40. - PubMed
    1. Labiris G, Giarmoukakis A, Sideroudi H, et al. Impact of keratoconus, cross-linking and cross-linking combined with photorefractive keratectomy on self-reported quality of life. Cornea. 2012;31:734–739. - PubMed

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