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Review
. 2012 Dec;28(12):1391-5; quiz 1396-8.
doi: 10.1097/PEC.0b013e318276fde2.

Ketamine, propofol, and ketofol use for pediatric sedation

Michelle J Alletag  1 , Marc A Auerbach, Carl R Baum
Affiliations
Review

Ketamine, propofol, and ketofol use for pediatric sedation

Michelle J Alletag et al. Pediatr Emerg Care. 2012 Dec.

Abstract

The use of a combination of ketamine and propofol (ketofol) for procedural sedation and analgesia in the emergency department setting shows promise as an agent that may minimize adverse effects of ketamine or propofol as single agents. This article provides a summary of current literature regarding ketofol. It also reviews the comparative pharmacokinetics, adverse effects, and dosing of ketamine, propofol, and ketofol as agents for procedural sedation and analgesia.

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