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. 2012;7(11):e50553.
doi: 10.1371/journal.pone.0050553. Epub 2012 Nov 30.

Vaccination rates among the general adult population and high-risk groups in the United States

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Vaccination rates among the general adult population and high-risk groups in the United States

Kathy Annunziata et al. PLoS One. 2012.

Abstract

Background: In order to adequately assess the effectiveness of vaccination in helping to control vaccine-preventable infectious disease, it is important to identify the adherence and uptake of risk-based recommendations.

Methods: The current project includes data from five consecutive datasets of the National Health and Wellness Survey (NHWS): 2007 through 2011. The NHWS is an annual, Internet-based health questionnaire, administered to a nationwide sample of adults (aged 18 or older) which included items on vaccination history as well as high-risk group status. Vaccination rates and characteristics of vaccinees were reported descriptively. Logistic regressions were conducted to predict vaccination behavior from sociodemographics and risk-related variables.

Results: The influenza vaccination rate for all adults 18 years and older has increased significantly from 28.0% to 36.2% from 2007 to 2011 (ps<.05). Compared with those not at high risk (25.1%), all high-risk groups were vaccinated at a higher rate, from 36.8% (pregnant women) to 69.7% (those with renal/kidney disease); however, considerable variability among high-risk groups was observed. Vaccination rates among high-risk groups for other vaccines varied considerably though all were below 50%, with the exception of immunocompromised respondents (57.5% for the hepatitis B vaccine and 52.5% for the pneumococcal vaccine) and the elderly (50.4% for the pneumococcal). Multiple risk factors were associated with increased rate of vaccination for most vaccines. Significant racial/ethnic differences with influenza, hepatitis, and herpes zoster vaccination rates were also observed (ps<.05).

Conclusions: Rates of influenza vaccination have increased over time. Rates varied by high-risk status, demographics, and vaccine. There was a pattern of modest vaccination rate increases for individuals with multiple risk factors. However, there were relatively low rates of vaccination for most risk-based recommendations and all fell below national goals.

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Conflict of interest statement

Competing Interests: The authors have read the journal’s policy and have the following conflicts. The National Health Wellness Survey is conducted annually by Kantar Health. KA and MD are current employees of Kantar Health. GlaxoSmithKline purchased access to the NHWS data and funded the analysis and preparation of this manuscript. AR, HDB, and GK are current employees of GlaxoSmithKline. This paper includes no information on marketed products so there are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Figures

Figure 1
Figure 1. Percentage of high-risk groups who have been vaccinated.
N/A: risk category is not applicable to this particular vaccine according to the ACIP; immunocompromised: (HIV/AIDS); CHD: Congestive heart failure, heart attack, angina, arrhythmia; lung conditions: COPD/emphysema/bronchitis, asthma; liver disease: Hepatitis B, Hepatitis C, chronic liver disease, cirrhosis; renal/kidney disease: chronic kidney disease, moderate-severe renal disease; MSM: men who have sex with men; Any high risk group: membership in any of the high-risk categories above.
Figure 2
Figure 2. Vaccination rates by number of risk factors.

References

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