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Case Reports
. 2012 Jul-Sep;8(3):3-7.
doi: 10.14797/mdcj-8-3-3.

The amyloidoses: clinical features, diagnosis and treatment

Kelty R Baker  1 , Lawrence Rice
Affiliations
Case Reports

The amyloidoses: clinical features, diagnosis and treatment

Kelty R Baker et al. Methodist Debakey Cardiovasc J. 2012 Jul-Sep.

Abstract

Amyloidosis is a rare disorder in which insoluble amyloid proteins are deposited in body organs, causing abnormal protein build-up in tissues and eventually leading to organ dysfunction and death. It affects less than 200,000 people in the United States, classifying it as a rare disease according to the National Institutes of Health. Definitive determination of the underlying protein is critical since prognosis and treatment of amyloidosis can vary widely depending on the responsible protein. The following paper describes the various types and clinical features of amyloidosis and provides an overview of current diagnostic tools and therapies.

Keywords: AL amyloidosis; amyloidoses; hematopoietic stem cell transplantation; light chain amyloidosis; multiple myeloma.

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