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. 2013 Mar 1;18(2):e201-6.
doi: 10.4317/medoral.18035.

Oral lichen planus: a retrospective study of 633 patients from Bucharest, Romania

Serban Tovaru  1 , Ioanina Parlatescu, Carmen Gheorghe, Mihaela Tovaru, Mariana Costache, Andrea Sardella
Affiliations

Oral lichen planus: a retrospective study of 633 patients from Bucharest, Romania

Serban Tovaru et al. Med Oral Patol Oral Cir Bucal. .

Abstract

Objective: In this retrospective study, patients' medical records were reviewed to investigate the profiles of 633 OLP cases in a group of Romania.

Material and methods: In this retrospective study, the following clinical data were obtained from the medical charts of patients: gender, age, clinical presentation of OLP, site affected, presence of symptoms, extraoral manifestations of lichen planus, presence of systemic diseases, and history of medications.

Results: Most (78.67%) OLP patients were female and the mean age at presentation was 52 years. The white type of the disease (reticular/papular/plaque lesions) was the main form encountered in this sample (48.97%). Among patients with available hepatitis C virus test results, 9.6% were serum-positive. OLP was associated with gallbladder disease (i.e. cholecystitis, cholelithiasis) in 19% of patients. Six patients (0.95%) developed squamous cell carcinoma at a site with confirmed OLP lesions.

Conclusions: To the best of our knowledge, no similar study has been conducted in a Romanian population. The present investigation revealed the predominance of OLP among middle-aged white women and the prevalence of bilateral involvement of the buccal mucosa with reticular white lesions. Anti-HCV circulating antibodies were more common in patients with OLP than in the general population and, notably, OLP was associated with gallbladder disease (cholecystitis, cholelithiasis) in 19% of patients.

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Figures

Figure 1
Figure 1
Reticular white lesions on the left buccal mucosa of a male patient.
Figure 2
Figure 2
Lingual involvement of the same patient of Figure 2.
See this image and copyright information in PMC

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