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. 2013 Apr;123(4):265-8.
doi: 10.3109/00207454.2012.756876. Epub 2013 Jan 29.

Human serum amyloid A (SAA) protein changes in acute epilepsy patients

Guifen Li  1 , Fang Ren, Jinhua Yao, Mingying Wang, Xianjun Feng, Dong Liu
Affiliations

Human serum amyloid A (SAA) protein changes in acute epilepsy patients

Guifen Li et al. Int J Neurosci. 2013 Apr.

Abstract

Previously, there is no study looking at serum biomarkers for epilepsy. Epilepsy can trigger neuroinflammation events, and serum amyloid A (SAA) is one biomarker as acute-phase protein in multiple diseases. In present study, we detected serum SAA peak in epileptic patients with mass spectrometry and quantified with enzyme-linked immunosorbent assay measurement. The results suggested that in acute phase of epilepsy, the serum SAA increased, but after 3 months of treatment, the SAA peak was disappeared. In conclusion, the study provided values of proteomic diagnosis of epilepsy.

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