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Case Reports
. 2012 Dec 12:2012:bcr2012006348.
doi: 10.1136/bcr-2012-006348.

Antiphospholipid syndrome presenting as pulmonary thrombosis and pancreatitis in a young man

Sanat Phatak  1 , Neelam Redkar, Meenakshi Amit Patil, Niteen D Karnik
Affiliations
Case Reports

Antiphospholipid syndrome presenting as pulmonary thrombosis and pancreatitis in a young man

Sanat Phatak et al. BMJ Case Rep. .

Abstract

The antiphospholipid syndrome and protein-S deficiency are known prothrombotic conditions. The confirmation of the latter in a patient with a recent antiphospholipid syndrome-associated thrombosis may be difficult as protein-S levels are low in a patient in the wake of recent thrombosis, antiphospholipid antibodies themselves may be targeted against protein-S and oral anticoagulation with warfarin may further bring down protein-S levels. We report a case of a 29-year-old man presenting with widespread unprovoked thrombosis in the form of pulmonary thromboembolism, neck vein thrombosis and pancreatitis. He was found to have antiphospholipid syndrome with low protein-S levels on two occasions. He was anticoagulated with heparin and improved over a 24-day hospital stay marred by the development of an exudative pleural effusion.

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Figures

Figure 1
Figure 1
Thrombosis of inferior branches of left and right pulmonary arteries.
Figure 2
Figure 2
CT chest image showing wedge-shaped ground glass opacities suggestive of pulmonary infarction.
See this image and copyright information in PMC

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