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. 1990 Apr;84(5):455-8.
doi: 10.1007/BF00195819.

Trophoblast glycoprotein recognised by monoclonal antibody 5T4 maps to human chromosome 6q14-q15

J M Boyle  1 , K H Grzeschik, P R Heath, J E Morten, P L Stern
Affiliations

Trophoblast glycoprotein recognised by monoclonal antibody 5T4 maps to human chromosome 6q14-q15

J M Boyle et al. Hum Genet. 1990 Apr.

Abstract

Human X rodent hybrids were stained by indirect immunofluorescence with 5T4, a murine monoclonal antibody that recognises a 72 kdalton glycoprotein expressed by human trophoblasts and a very restricted range of adult tissues; they were analysed by flow cytometry. Concordance analysis supported by segregation data allowed assignment of the gene controlling glycoprotein expression (M6P1) to chromosome 6. Similar analysis with translocation hybrids gave a regional assignment to 6q14-q15. M6P1 is distinct from NT5, coding for 5' nucleotidase, which maps to the same region.

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References

    1. Cytogenet Cell Genet. 1987;46(1-4):11-28 - PubMed
    1. Br J Cancer. 1990 Jan;61(1):89-95 - PubMed
    1. Hum Genet. 1988 Dec;81(1):88-92 - PubMed
    1. Biochim Biophys Acta. 1978 Apr 20;508(3):565-70 - PubMed
    1. Int J Cancer. 1990 Jan 15;45(1):179-84 - PubMed

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