The soothing touch: microglial contact influences neuronal excitability
- PMID: 23237948
- DOI: 10.1016/j.devcel.2012.11.015
The soothing touch: microglial contact influences neuronal excitability
Abstract
Resting microglial cells in the brain scan their environment with their processes, primed to react to injury and disease. In this issue of Developmental Cell, Li and colleagues (2012) report that resting microglia also react to physiological neuronal activity, sending their processes toward highly active neurons to regulate their excitability.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Reciprocal regulation between resting microglial dynamics and neuronal activity in vivo.Dev Cell. 2012 Dec 11;23(6):1189-202. doi: 10.1016/j.devcel.2012.10.027. Epub 2012 Nov 29. Dev Cell. 2012. PMID: 23201120
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