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. 1990 Mar;29(2):177-83.
doi: 10.1097/00004583-199003000-00004.

A family history study of neuropsychiatric disorders in the adult siblings of autistic individuals

J Piven  1 , J Gayle, G A Chase, B Fink, R Landa, M M Wzorek, S E Folstein
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Free article

A family history study of neuropsychiatric disorders in the adult siblings of autistic individuals

J Piven et al. J Am Acad Child Adolesc Psychiatry. 1990 Mar.
Free article

Abstract

The family history method was used to obtain developmental, social, and psychiatric histories on the 67 adult siblings of 37 autistic probands. Two of 67 siblings (3.0%) were autistic, three siblings (4.4%) had severe social dysfunction and isolation, 10 (15%) had cognitive disorders, and 10 (15%) had received treatment for affective disorder. This study is the first to investigate the frequency of disorders in the adult siblings of autistic probands. These results suggest aggregation of a variety of neuropsychiatric disorders in the siblings of autistic individuals.

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Comment in

  • Biological liability in families with autism.
    Abramson RK, Wright HH, Cuccaro ML, Lawrence LG, Babb S, Pencarinha D, Marsteller F, Harris EC. Abramson RK, et al. J Am Acad Child Adolesc Psychiatry. 1992 Mar;31(2):370-1. doi: 10.1097/00004583-199203000-00030. J Am Acad Child Adolesc Psychiatry. 1992. PMID: 1564043 No abstract available.

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