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. 1990 Jan;5(1):71-4.
doi: 10.1093/oxfordjournals.humrep.a137045.

Variation in the cholesterol/phospholipid ratio in human spermatozoa and its relationship with capacitation

K Hoshi  1 , T Aita, K Yanagida, N Yoshimatsu, A Sato
Affiliations

Variation in the cholesterol/phospholipid ratio in human spermatozoa and its relationship with capacitation

K Hoshi et al. Hum Reprod. 1990 Jan.

Abstract

The cholesterol/phospholipid (C/PL) ratio was determined for spermatozoa from eight men with normal semen parameters. There was a close correlation between the C/PL ratio and the rate of sperm capacitation as assessed by the hamster egg penetration test. A lower C/PL ratio correlated with a faster capacitation time. This supports the notion that the loss or reduction of membrane cholesterol constitutes an important step of capacitation in human spermatozoa.

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