Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Dec 17;289(16):1267-70.

[5-Bromodeoxyuridine inhibition of the transformation of Rous sarcoma virus-infected chicken cells]

[Article in French]
A Goldé, D Rouillard
  • PMID: 232429

[5-Bromodeoxyuridine inhibition of the transformation of Rous sarcoma virus-infected chicken cells]

[Article in French]
A Goldé et al. C R Seances Acad Sci D. .

Abstract

The transformation of Rous-Sarcoma-Virus-infected synchronized Chicken cells is prevented when 5-bromodeoxyuridine is added for 3 hrs. at time of the peak of the first S phase following infection. Virus progeny is normally released. The inhibitory effect of BrdU is reversed by simultaneous addition of thymidine, but not by that of deoxyuridine. Hence, the inhibition of the transformation seems to result from the incorporation of the analogue into the nuclear DNA.

PubMed Disclaimer

Publication types

Substances