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. 2012 Oct;29(4):384-7.
doi: 10.4103/0970-2113.102841.

Primary monophasic synovial sarcoma lung with brain metastasis diagnosed on transthoracic FNAC: Report of a case with literature review

Paras Nuwal  1 , Ramakant Dixit, Narender Singh Shah, Anil Samaria
Affiliations

Primary monophasic synovial sarcoma lung with brain metastasis diagnosed on transthoracic FNAC: Report of a case with literature review

Paras Nuwal et al. Lung India. 2012 Oct.

Abstract

Synovial sarcoma is highly malignant tumor of soft tissues, occurring chiefly in the extremities and limb girdle with a propensity for local recurrence and sometimes metastases to the lungs. Primary synovial sarcoma arising in the lungs is rare and brain metastasis as presentation is further uncommon. We report a case of primary monophasic synovial sarcoma lung presenting with brain metastasis in a 35-year-old male patient. The diagnosis was made on percutaneous transthoracic needle aspiration from left-sided pulmonary mass and later confirmed by immunohistochemistry. The utility of preoperative diagnosis by percutaneous aspiration cytology is also stressed.

Keywords: Brain metastasis; fine needle aspiration cytology; monophasic synovial sarcoma lung.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
X-ray chest PA view showing left upper lobe mass lesion
Figure 2
Figure 2
CT scan chest showing a large, soft tissue density mass at left upper lobe lung with central necrotic areas
Figure 3
Figure 3
Photomicrograph of fine needle aspirate from lung lesion showing pleomorphic bipolar spindle cells with oval to spindled nuclei (H and E, ×200)
Figure 4
Figure 4
Photomicrograph of histological sections of brain mass tissue showing typical features of metastatic monophasic synovial carcinoma (H and E, ×200)
See this image and copyright information in PMC

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