doi: 10.1007/s11274-012-1233-9.
Epub 2012 Dec 18.
Isolation and characterization of three fungi with the potential of transforming glycyrrhizin
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- PMID: 23247917
- DOI: 10.1007/s11274-012-1233-9
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Isolation and characterization of three fungi with the potential of transforming glycyrrhizin
World J Microbiol Biotechnol.
2013 May.
Abstract
Three fungi with different types of transformation of glycyrrhizin (GL) were isolated from the soil samples of glycyrrhiza glabra planting area in China. According to their morphologies and 18 S rDNA gene sequence analysis, the three fungi were identified and named as Penicillium purpurogenum Li-3, Aspergillus terreus Li-20 and Aspergillus ustus Li-62. Transforming products analysis by TLC and HPLC-MS indicated that P. purpurogenum Li-3, A. terreus Li-20 and A. ustus Li-62 could stably transform GL into GAMG, GAMG and GA, and GA, respectively. P. purpurogenum Li-3 was especially valuable to directly prepare GAMG for applications in the pharmaceutical industry.
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