Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2012 Sep;4(3):172-4.
doi: 10.4103/0974-7796.102667.

Leiomyoma of the urinary bladder in asymptomatic women

Havva Erdem  1 , Umran Yildirim, Ali Tekin, Ali Kayikci, Ali Kemal Uzunlar, Cem Sahiner
Affiliations
Case Reports

Leiomyoma of the urinary bladder in asymptomatic women

Havva Erdem et al. Urol Ann. 2012 Sep.

Abstract

Most bladder tumors are derived from the urothelium. Benign mesenchymal tumors are rare. Leiomyomas account for less than 0.43% of all bladder tumors. Genitourinary leiomyomata may arise in any anatomic structure containing smooth muscle. They have been reported to involve single or multiple organs. Since they may also mimic malignant lesions, they should always be considered in the differential diagnosis of any pelvic mass, with a possibility of being asymptomatic and discovered incidentally by radiographic imaging. We, herein, report a case illustrating clinical and pathological features in particular immunohistochemistry, and discuss its etiology and differential diagnosis.

Keywords: Differential diagnosis; leiyomyoma; leiyomyosarcomas.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None

Figures

Figure 1
Figure 1
MRI of the pelvis shows intraluminal polypoidal enhancing mass projecting into the bladder lumen
Figure 2
Figure 2
MRI of the pelvis shows enhancing mass projecting into the bladder lumen (second MRI)
Figure 3
Figure 3
Microscopically, the tumor was composed of whorled interlacing fascicles of typical smooth muscle cells without pleomorphism or mitotic figures, and the lumen was covered with urotelial epithelial cells (H and E, ×200)
Figure 4
Figure 4
Immunohistochemically, the tumor cells were positive for smooth muscle actin (IHC stain, ×200)
Figure 5
Figure 5
Immunohistochemically, the tumor cells were negative for CD117 (IHC stain, ×200)
See this image and copyright information in PMC

References

    1. Gomez Vegas A, Silmi Moyano A, Fernandez Lucas C, Blazquez Izquierdo J, Delgado Martin JA, Corral Rosillo J, et al. Leiomyoma of the lower urinary tract. Arch Esp Urol. 1991;44:795–8. - PubMed
    1. Saunders SE, Conjeski JM, Zaslau S, Williams J, Kandzari SJ. Leiomyoma of the urinary bladder presenting as urinary retention in the female. Can J Urol. 2009;16:4762–4. - PubMed
    1. Chassagne S, Bernier PA, Haab F, Roehrborn CG, Reisch JS, Zimmern PE. Proposed cutoff values to define bladder outlet obstruction in women. Urology. 1998;51:408–11. - PubMed
    1. Brande SD, Katz S. In: Non-epithelial tumors of the ureters and urinary bladder, in Uropathology. Hill GS, editor. Churchill Livingstone; 1989. pp. 861–72.
    1. McLukas B, Stein J. Bladder leiomyoma: A rare cause of pelvic pain. Am J Obstet Gynecol. 1985;153:896. - PubMed

Publication types