[Advance in the research of platelet-rich plasma in burn treatment]

Abstract

Platelet-rich plasma (PRP) is the plasma derived from the repeatedly centrifuged whole blood, and it contains high concentration of platelets. The growth factors and concentrated platelets in PRP play important roles in proliferation, division, and differentiation of cells, and wound repair. In the past, PRP was used in the treatment of bone fracture, bone defect, soft tissue injury, and refractory wound. In recent years, it had been used in burn treatment, but it provoked some disputes. This article reviews the advance in the research of PRP in burn treatment and discusses the problems in its clinical application.