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. 2012 Nov;45(4):358-61.
doi: 10.5946/ce.2012.45.4.358. Epub 2012 Nov 30.

ESD Hands-on Course Using Ex Vivo and In Vivo Models in South Korea

Gene Hyun Bok  1 , Joo Young Cho
Affiliations

ESD Hands-on Course Using Ex Vivo and In Vivo Models in South Korea

Gene Hyun Bok et al. Clin Endosc. 2012 Nov.

Abstract

Endoscopic submucosal dissection (ESD) is an established treatment for gastric neoplasias especially in regions with a high volume of gastric cancer. Although ESD has many advantages over endoscopic mucosal resection, ESD is technically more difficult and can result in severe complications. Therefore establishment of an effective training system is required to help endoscopists climb the ESD learning curve. Although a standard training system for ESD remains to be established, some centers are incorporating ex vivo and/or in vivo animal models to provide a safe and effective means of ESD training. However, it is unknown if these animal models are more effective than other programs. Moreover the efficacy of the animal model may vary according to socio-economic status and the volume of gastric cancer. In this article we introduce the basic and advanced ESD training model using the ex vivo and in vivo animal model from South Korea and review the associated literature from other regions.

Keywords: Endoscopic submucosal dissection; Endoscopic submucosal dissection training; Ex vivo model; In vivo model.

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Conflict of interest statement

The authors have no financial conflicts of interest.

Figures

Fig. 1
Fig. 1
Preparation of the ex vivo porcine stomach. The stomach is irrigated thouroghly within 24 hours of euthanization.
Fig. 2
Fig. 2
Preparation of the ex vivo porcine model. The esophagus is connected to an overtube and fixed within a plastic frame.
Fig. 3
Fig. 3
Configuration of ex vivo model. The duodenum is clamped using forceps and the stomach is placed inside the frame on top of a metal plate and return electrode for electrical current conduction.
Fig. 4
Fig. 4
The Korean Society of Gastrointestinal Endoscopy hands-on course using the live in vivo porcine model.
See this image and copyright information in PMC

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