Author’s response: Humans, fruit flies, and automatons
- PMID: 23251931
- DOI: 10.1017/s0140525x12001501
Author’s response: Humans, fruit flies, and automatons
Abstract
My response is divided into four sections: (1) is devoted to a potpourri of commentaries that are essentially in agreement with the substance of my target article (with one exception); in (2) I address, in response to one of the commentaries, several issues relating to the use of candidate gene association studies in behavior genetics (in particular those proposing a specific G × E interaction); in (3) I provide a detailed response to several defenses of the twin study methodology; and in (4) I conclude with several reflections on that methodology and the conception of human nature it has fostered.
Comment on
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Clinicians learn less and less about more and more until they know nothing about everything; researchers learn more and more about less and less until they know everything about nothing: discuss.Behav Brain Sci. 2012 Oct;35(5):358-9. doi: 10.1017/S0140525X12001367. Behav Brain Sci. 2012. PMID: 23095379
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Is behavioral genetics 'too-big-to-know' science?Behav Brain Sci. 2012 Oct;35(5):360. doi: 10.1017/S0140525X12001331. Behav Brain Sci. 2012. PMID: 23095380
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Twin and family studies are actually more important than ever.Behav Brain Sci. 2012 Oct;35(5):361. doi: 10.1017/S0140525X12000969. Behav Brain Sci. 2012. PMID: 23095381
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Heritability estimates in behavior genetics: wasn't that station passed long ago?Behav Brain Sci. 2012 Oct;35(5):361-2. doi: 10.1017/S0140525X12000970. Behav Brain Sci. 2012. PMID: 23095382
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Postgenomics and genetic essentialism.Behav Brain Sci. 2012 Oct;35(5):362-3. doi: 10.1017/S0140525X12000982. Behav Brain Sci. 2012. PMID: 23095383
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Non-Mendelian etiologic factors in neuropsychiatric illness: pleiotropy, epigenetics, and convergence.Behav Brain Sci. 2012 Oct;35(5):363-4. doi: 10.1017/S0140525X12001392. Behav Brain Sci. 2012. PMID: 23095384 Free PMC article.
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Is genomics bad for you?Behav Brain Sci. 2012 Oct;35(5):364-5. doi: 10.1017/S0140525X12000994. Behav Brain Sci. 2012. PMID: 23095385
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Preventing a paradigm shift: a plea for the computational genome.Behav Brain Sci. 2012 Oct;35(5):365-6. doi: 10.1017/S0140525X12001355. Behav Brain Sci. 2012. PMID: 23095386
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Biology trumps statistics in the postgenomic era.Behav Brain Sci. 2012 Oct;35(5):366-7. doi: 10.1017/S0140525X12001008. Behav Brain Sci. 2012. PMID: 23095387
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Affirmation of a developmental systems approach to genetics.Behav Brain Sci. 2012 Oct;35(5):367. doi: 10.1017/S0140525X12001124. Behav Brain Sci. 2012. PMID: 23095388
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Genetic sensitivity to the environment, across lifetime.Behav Brain Sci. 2012 Oct;35(5):368. doi: 10.1017/S0140525X1200101X. Behav Brain Sci. 2012. PMID: 23095389
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A call for an expanded synthesis of developmental and evolutionary paradigms.Behav Brain Sci. 2012 Oct;35(5):368-9. doi: 10.1017/S0140525X12001021. Behav Brain Sci. 2012. PMID: 23095390
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From gene activity to behavior (and back again).Behav Brain Sci. 2012 Oct;35(5):369-70. doi: 10.1017/S0140525X12001033. Behav Brain Sci. 2012. PMID: 23095391
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The fate of heritability in the postgenomic era.Behav Brain Sci. 2012 Oct;35(5):370-1. doi: 10.1017/S0140525X12001045. Behav Brain Sci. 2012. PMID: 23095392
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A developmental science commentary on Charney's "Behavior genetics and postgenomics".Behav Brain Sci. 2012 Oct;35(5):371-2. doi: 10.1017/S0140525X12001057. Behav Brain Sci. 2012. PMID: 23095393
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Assumptions in studies of heritability and genotype-phenotype association.Behav Brain Sci. 2012 Oct;35(5):372-3. doi: 10.1017/S0140525X12001380. Behav Brain Sci. 2012. PMID: 23095394
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Estimating the actual subject-specific genetic correlations in behavior genetics.Behav Brain Sci. 2012 Oct;35(5):373-4. doi: 10.1017/S0140525X12001069. Behav Brain Sci. 2012. PMID: 23095395
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Gene-independent heritability of behavioural traits: don't we also need to rethink the "environment"?Behav Brain Sci. 2012 Oct;35(5):374-5. doi: 10.1017/S0140525X12001070. Behav Brain Sci. 2012. PMID: 23095396
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Relational developmental systems: a paradigm for developmental science in the postgenomic era.Behav Brain Sci. 2012 Oct;35(5):375-6. doi: 10.1017/S0140525X12001082. Behav Brain Sci. 2012. PMID: 23095397
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The history of the nature/nurture issue.Behav Brain Sci. 2012 Oct;35(5):376-7. doi: 10.1017/S0140525X12001094. Behav Brain Sci. 2012. PMID: 23095398
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Epigenetic regulation of brain-derived neurotrophic factor: implications in neurodevelopment and behavior.Behav Brain Sci. 2012 Oct;35(5):377-8. doi: 10.1017/S0140525X12001100. Behav Brain Sci. 2012. PMID: 23095399
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Parental brain and socioeconomic epigenetic effects in human development.Behav Brain Sci. 2012 Oct;35(5):378-9. doi: 10.1017/S0140525X12001112. Behav Brain Sci. 2012. PMID: 23095400 Free PMC article.
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Neogenomic events challenge current models of heritability, neuronal plasticity dynamics, and machine learning.Behav Brain Sci. 2012 Oct;35(5):379-80. doi: 10.1017/S0140525X12001379. Behav Brain Sci. 2012. PMID: 23095401
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A straw man's neogenome.Behav Brain Sci. 2012 Oct;35(5):380-1. doi: 10.1017/S0140525X12001343. Behav Brain Sci. 2012. PMID: 23095402