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. 2013 Mar;51(3):993-4.
doi: 10.1128/JCM.02863-12. Epub 2012 Dec 19.

Real-time PCR quantification of Methanobrevibacter oralis in periodontitis

Amélie Bringuier  1 , Saber Khelaifia, Hervé Richet, Gérard Aboudharam, Michel Drancourt
Affiliations

Real-time PCR quantification of Methanobrevibacter oralis in periodontitis

Amélie Bringuier et al. J Clin Microbiol. 2013 Mar.

Abstract

A real-time PCR assay developed to quantify Methanobrevibacter oralis indicated that its inoculum significantly correlated with periodontitis severity (P = 0.003), despite a nonsignificant difference in prevalence between controls (3/10) and patients (12/22) (P = 0.2, Fisher test). The M. oralis load can be used as a biomarker for periodontitis.

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